The patent-pending S-Trap™ brings universal, simple and inexpensive sample preparation to bottom-up proteomics. In about an hour you can concentrate, clean up and digest any sample from micrograms to milligrams.
Tryp-N™ is an engineered metalloprotease which cuts in front of arginine and lysine developed at Cold Spring Harbor Laboratory (CSHL). By placing all basic centers of peptides (the amino terminus and side chains of K/R) at the N-termini of peptides, you observe complementary b-ions and gain sensitivity.
Simplify™ is for quantitative pathway analysis what MASCOT is for identifying proteins: data in and pathways out. Like MASCOT, it uses unbiased statistics which make very few assumptions about your data.
Protein preparation products will soon be available from the microgram to multiple milligram scale. Large scale is particularly useful for those doing pre-enrichment for example in phosphopeptide or SISCAPA/immunoaffinity analysis.